Introduction

Caricef syrup is composed of cefixime trihydrate, cefixime trihydrate is a type of antibiotic medication used to treat a variety of bacterial infections. It belongs to a class of drugs known as cephalosporins and works by stopping the growth and spread of bacteria in body.


Uses of Caricef syrup

Cefixime trihydrate syrup is a prescription medication used to treat bacterial infections. Some of the common uses of cefixime trihydrate syrup include:

  • Upper respiratory tract infections: cefixime trihydrate syrup is used to treat infections of the pharynx (throat), tonsils (tonsillitis), and sinuses (sinusitis).
  • Urinary tract infections: the syrup is used to treat infections of the bladder (cystitis), urethra (urethritis), and kidneys (pyelonephritis).
  • Gastrointestinal infections: cefixime trihydrate syrup may be used to treat certain types of diarrheas caused by bacteria, such as traveler's diarrhea.
  • Sexually transmitted infections: the syrup may be used to treat some sexually transmitted infections, such as gonorrhea.

It is important to note that cefixime trihydrate syrup should only be used to treat bacterial infections only not for viral infections.

Drug interactions

Cefixime trihydrate is an oral cephalosporin antibiotic. It has the potential to interact with several other drugs. Some common drug interactions of cefixime trihydrate include:

  • Antacids: cefixime trihydrate should not be taken with antacids as they can reduce its absorption.
  • Probenecid: probenecid can increase the levels of cefixime in the body, leading to increased risk of side effects.
  • Blood-thinning medications (e.g., warfarin): cefixime trihydrate may increase the risk of bleeding when taken with blood-thinning medications.
  • Other antibiotics: taking cefixime trihydrate with certain other antibiotics can alter the effectiveness of either drug.

Disease interactions

Some of the disease interactions with cefixime trihydrate syrup include:

  • Liver disease: patients with liver disease may have an increased risk of developing side effects from cefixime trihydrate syrup.
  • Kidney disease: cefixime trihydrate is eliminated from the body by the kidneys, so patients with kidney disease may require a lower dose of the medication.
  • Blood clotting disorders: patients with blood clotting disorders may have an increased risk of bleeding when taking cefixime trihydrate syrup.
  • Allergies: patients who are allergic to cephalosporin antibiotics or any other ingredient in cefixime trihydrate syrup should not take the medication.

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Food interactions

Cefixime trihydrate syrup, like all medications, can interact with certain foods and drinks. Some of the food interactions with cefixime trihydrate syrup include:

  • Dairy products: cefixime trihydrate syrup should not be taken with dairy products, such as milk or yogurt, as they can reduce its absorption. It is recommended to take the medication at least two hours before or after dairy products.
  • Antacids: antacids, such as calcium carbonate or magnesium hydroxide, should not be taken with cefixime trihydrate syrup as they can reduce its absorption.
  • Iron supplements: cefixime trihydrate syrup may decrease the absorption of iron supplements, so it is recommended to take iron supplements at least two hours before or after taking the medication.

Side effects of Caricef syrup

Cefixime trihydrate syrup, like all medications, can cause side effects in some people. Some usual side effects of cefixime trihydrate syrup include:

  • Nausea and vomiting
  • Diarrhea
  • Stomach pain or discomfort
  • Headache
  • Rash or itching
  • Dizziness
  • Vaginal itching or discharge (in women)

Complicated side effects of cefixime trihydrate syrup are rare, but they can occur. These include:

  • Allergic reactions: symptoms may include hives, itching, swelling, difficulty breathing, and/or a severe rash.
  • Bleeding: cefixime trihydrate syrup may increase the risk of bleeding, especially when taken with blood-thinning medications.
  • Seizures: seizures have been reported in some people taking cefixime trihydrate syrup.

Dosing information

  • The dosing of cefixime trihydrate syrup is based on various factors, including age, weight, and the type and severity of the infection being treated. It is important to take cefixime trihydrate syrup exactly as prescribed by your doctor. Do not change the dose or frequency of the medication without consulting your doctor.
  • The usual adult dose of cefixime trihydrate syrup is 400 mg, taken orally once a day or divided into two doses per day. The pediatric dose of cefixime trihydrate syrup depends on the age and weight of the child, and ranges from 8 mg to 20 mg per kilogram of body weight per day.
  • It is important to complete the full course of cefixime trihydrate syrup, even if you feel better, as stopping the medication too soon can cause the infection to recur or become resistant to the medication.

Packaging

Cefixime trihydrate syrup is packaged in a bottle made of glass or plastic. The size of the bottle can vary, but typically it ranges from 100 ml to 200 ml. The bottle is usually sealed with a child-resistant cap to prevent accidental ingestion by children. The packaging of cefixime trihydrate syrup should always include a label that provides information about the medication, including its active ingredient (cefixime trihydrate), dosage form (syrup), strength, and expiration date.


In addition, the packaging should include instructions for use and storage, as well as a list of potential side effects. It is important to keep cefixime trihydrate syrup in its original packaging and store it at room temperature, away from moisture and light. The medication should be discarded after its expiration date.


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Storage

  • Cefixime trihydrate syrup should be stored at room temperature, away from moisture and light. The ideal storage temperature for cefixime trihydrate syrup is between 15°c to 30°c. The medication should be kept in its original packaging and should not be stored in the refrigerator or freezer.
  • In addition, it is important to keep cefixime trihydrate syrup out of reach of children, as it can be dangerous if ingested accidentally. The medication should be disposed of properly after its expiration date to prevent potential harm to children and the environment.
  • It is recommended to keep a record of the medications you have at home and their expiration dates, so that you can dispose of any outdated or unused medications properly.

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Source: https://instacare.pk/blog/caricef-syrup-uses-side-effects-and-price-in-pakistan