Another brand name that people use in place of erythromycin is Erythrocin. It is, in fact a macrolide antibiotic that is prevalently used in treatment of different bacterial infections in organisms. It can be administered both without admission to the hospital and with hospitalization. Understanding its use, its side effects and things people are likely to ask are useful to anyone who may consider using the particular drug or is already using it.

 

What is Erythrocin?

Because Erythrocin thus breaks the protein synthesizing process in bacteria, there is no way that these bacteria can reproduce while using this drug. The antibiotic is quite effective against thousands of different forms of bacteria, and some of these cannot be eradicated by other types of antibiotics. Erythromycin is distributed in tablets, caplets, topical suspension, ointment, and lyophilized powder for intravenous preparation.


Erythrocin is going to bind to the 50S ribosomal subunit of the bacterium, hence preventing bacterial protein synthesis. Therefore, this renders it impossible for the bacteria to synthesize proteins to either grow or function that would kill them from the bacterial cell. For that reason, it becomes a bacteriostatic antibiotic-erythromycin slows the growth of bacteria but kills no bacteria entirely.

 

Uses of Erythrocin

 

Respiratory Tract Infections

It is ordinarily utilized in respiratory system, influenza, pneumonia, bronchitis and sinusitis. Erythrocin is highly effective for the following infections: , Streptococcal pneumonia, Haemophilus influenza, and Mycoplasma pneumonia isofrank infections. It is most used on patients with complications of reactions on antibiotics especially penicillin.

 

Skin Infections

This antibiotic is used when treating skin infections which comprises of acne and cellulitis. Acne is also cured by taking this antibiotic orally for skin use or consumption as much as possible to reduce bacteria on human skin in other to promote rapid healing.

 

Otitis

Erythrocin is used in the management of middle ear infections, otitis media in children and adults. It is administered when patients cannot be initiated on first line antibiotics such as amoxicillin as there is a form of allergy or resistance present.

 

Gastrointestinal Infections

Erythrocin is used in treating infections within the gastrointestinal tract caused by some forms of bacteria which include Campylobacter and Helicobacter pylori. The latter form is strongly implicated since it is highly associated with peptic ulcers. A combination of the above medication is usually given together with a multidrug therapy for H. pylori.

 

Sexually Transmitted Infections

Erythrocin at times is given for STDs for instance Chlamydia. Also, patients with penicillin allergies are administered cephalexin; the main regimen is azithromycin or erythromycin if the patient is allergic to azithromycin.

 

Other Uses

Erythrocin has been used in the treatment of other conditions include:

Prophylaxis of endocarditis: In coordination with the patient’s cardiac disease, all patients receive erythromycin before any dental work in order to prevent bacterial endocarditis.

Chronic bronchitis: In patients with chronic bronchitis, erythromycin will reduce the frequency of exacerbations.


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Dosage and Administration

Dosage of Erythrocin is administered depending on the type of infection, age, and general health condition of the patient. He should take it strictly following the schedule of his health provider. It could be administered both with and without food. But to attain the best efficacy, constant dosing should be followed. This ensures that the concentration of the drug in the body will be steady.


For adults, the oral use require dosage of 250 to 500 mg every 6 to 12 hour for mild to moderate infections depending on the type of infection.. In IV, the daily dosages will be between one and four grams and the dosages are likely to be divided into more than one administration.

 

Pediatric Dosage

It is age-dependent on the patients and generally administered based on body weight. Doctors claim that it is usually given to children in divided doses where the daily dose falls between 30 to 50 milligrams per kilogram of body weight.

 

Side Effects of Erythrocin

Erythrocin is usually well tolerated; however, some patients may have side effects. Side effects awareness is very crucial for proper application and safe implementation. .

 

Common Side Effects

 

Gastrointestinal Problems:

Nausea and Vomiting: The majority of the customers mentioned they had gastric problems because that was what they referred their symptoms as being: nausea and vomiting. In what appears to be an attempt to avert the side effects of erythromycin the dose should be taken with food.


  • Diarrhea: Some patients may have diarrhea from mild to severe. In any case, they should be seen by a healthcare provider. If left untreated or worse, a patient should see a doctor.
  • Allergic Reactions: A patient, although a rare condition may experience a hypersensitivity reaction to Erythrocin. The following symptoms can occur.
  • Rash or hives
  • Itching
  • Swelling of the face, lips, or throat
  • Trouble breathing

Any of these symptoms should be brought to the doctor's attention immediately.

  • Liver Disorders: Prolonged treatment with erythrocin, especially at high doses, may cause liver disorders. Liver disorders symptoms include:
  • Jaundice, or yellowing of the skin or eyes
  • Dark urine
  • Severe tiredness

Patients on prolonged erythromycin therapy may be subjected to periodic checkup of their liver function.

Heart Conditions: Erythrocin alters the heart rhythm causing QT prolongation among others. Symptoms may include:


  • Flutter
  • Dizziness
  • Fainting

Patients with heart disease conditions should take heed and go for proper consultancy by their physicians, so they may be issued the drug by them.

 

Other Side Effects

 

Some other effects might be that;

  • Headache: Some people undergoing erythromycin sometimes have headaches.
  • Somnolence: Comatose caused by erythromycin consumers as drowsiness is achieved when using these medicines; so precaution is being used especially at times of handling heavy machines.
  • Skin Rash: A mild skin rash might develop and may subside once the drug is taken off.

Interactions with Other Drugs

Erythrocin may interact with other drugs. Such interactions can strengthen side effects or weaken efficacy

 

Common Drug Interactions

  • Warfarin
  • Statins
  • Other Antibiotics
  • Anticonvulsant

Special Precautions

 

Age Factors

Erythrocin is safe for adults and children. However, pediatric patients typically require special dosages depending on their weight and age; advice from a doctor is necessary when it comes to dosing pediatric patients.

 

Pre-existing Medications and Conditions

Take Erythrocin cautiously if a patient has a pre-existing history of diseases such as liver disease or heart rhythms. The patient needs close monitoring for safety.

 

Conclusion

Erythrocin has also proven to be efficient in curing most patients who are infected with bacterial strains - from pulmonary to dermatologic and even gastroenterological diseases. Still, though medication is effective enough, side effects and interactions have to be known by the one under the prescription as well. Consultation needs to be asked from the health worker before on taking such kind of medication or to discontinue the prescription itself.


Knowing how Erythrocin works and what is included in its administration helps to make the right decisions for yourself and your loved ones regarding their health. Appropriate dosing with observation for the presence of potential side effects can result in best benefitting the capacity that such a life-essential antibiotic may hold for a patient.


Please book an appointment with the Best Internal Medicine Specialist in Lahore, Karachi, Islamabad, and all major cities of Pakistan through InstaCare, or call our helpline at 03171777509 to find a verified doctor for your disease.