Introduction

Nilstat drops is a brand name for the medication nystatin, which is an antifungal medication used to treat a variety of fungal infections. In nilstat drops, nystatin, works by binding to the fungal cell membrane and preventing it from growing and reproducing.


Uses of nilstat drops

Here are some of the usual uses of nilstat drops are,

  • Oral thrush: Nilstat drops are commonly used to treat oral thrush, which is a fungal infection that affects the mouth and throat. This infection is caused by candida albicans and can cause symptoms such as white patches on the tongue and inside of the mouth, sore throat, and difficulty swallowing.
  • Skin fungal infections: Nilstat drops can be used to treat fungal infections of the skin, such as athlete's foot, jock itch, and ringworm. These infections are caused by different species of fungi and can cause symptoms such as redness, itching, and scaling of the affected area.
  • Vaginal candidiasis: Nilstat drops can be used to treat vaginal candidiasis, which is a fungal infection of the vagina caused by candida species. This infection can cause symptoms such as vaginal itching, burning, and discharge.
  • Nail fungal infections: Nilstat drops can be used to treat fungal infections of the nails, which are caused by various species of fungi. These infections can cause thickened, discolored nails that may be painful or difficult to trim.

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Drug interactions

Here are some examples of medications that may interact with nilstat drops:

  • Amphotericin b: Taking nilstat drops with amphotericin b, another antifungal medication, may increase the risk of kidney damage.
  • Immunosuppressants: Nilstat drops may interact with immunosuppressant medications, such as cyclosporine and tacrolimus, used to prevent rejection of transplanted organs. Nilstat drops may decrease the effectiveness of these medications.
  • Warfarin: Taking nilstat drops with warfarin, a blood-thinning medication, may increase the risk of bleeding. It is important to monitor blood clotting time and adjust the dose of warfarin as needed.
  • Oral contraceptives: Nilstat drops may decrease the effectiveness of oral contraceptives. It is recommended to use alternative forms of contraception while taking nilstat drops.
  • Antacids: Taking nilstat drops with antacids may decrease the absorption of nilstat drops and decrease its effectiveness.

Disease interactions

Here are some examples of disease interactions to consider before taking nilstat drops:

  • Liver disease: Individuals with liver disease may not be able to metabolize nilstat drops effectively, which may increase the risk of side effects. A healthcare professional may need to adjust the dosage of nilstat drops or consider an alternative treatment.
  • Kidney disease: Individuals with kidney disease may not be able to eliminate nilstat drops from their body effectively, which may increase the risk of side effects. A healthcare professional may need to adjust the dosage of nilstat drops or consider an alternative treatment.
  • Diabetes: Nilstat drops may contain sugar, which can increase blood sugar levels in individuals with diabetes. A healthcare professional may need to monitor blood sugar levels more closely while taking nilstat drops.
  • Gastrointestinal conditions: Individuals with gastrointestinal conditions, such as inflammatory bowel disease or malabsorption syndrome, may not be able to absorb nilstat drops effectively, which may decrease its effectiveness. A healthcare professional may need to adjust the dosage of nilstat drops or consider an alternative treatment.
  • Hiv infection: Individuals with hiv infection may have a higher risk of developing oral thrush and other fungal infections. Nilstat drops may interact with certain antiretroviral medications used to treat hiv, so it is important to inform a healthcare professional about all medications being taken.

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Food interactions

Here are some examples of food interactions to consider:

  • Grapefruit: Grapefruit and grapefruit juice may affect the absorption of certain medications, including nilstat drops. It is recommended to avoid grapefruit or grapefruit juice while taking nilstat drops.
  • Dairy products: Some individuals may experience decreased absorption of nilstat drops when taken with dairy products. It is recommended to take nilstat drops at least 2 hours before or after consuming dairy products.
  • High-fat foods: High-fat foods may decrease the absorption of nilstat drops. It is recommended to take nilstat drops on an empty stomach or with a light meal to increase absorption.
  • Alcohol: Alcohol may increase the risk of liver damage when taken with nilstat drops. It is recommended to avoid alcohol while taking nilstat drops.

Side effects of nilstat drops

Here are some usual side effects that may occur while taking nilstat drops:

  • Nausea or vomiting
  • Diarrhea
  • Stomach cramps
  • Rash or itching
  • Headache
  • Swelling or irritation of the mouth or tongue
  • Forgetting of taste or swap in taste

Rarely, nilstat drops may cause more complicated side effects, such as:

  • Difficulty breathing
  • Inflammation of the face, lips, tongue, or gullet
  • Severe diarrhea or stomach cramps
  • Yellowing of the skin or eyes
  • Dark urine
  • Unusual bleeding or bruising
  • Fever or chills

Dosing information

Here is some general dosing information for nilstat drops:

  • Oral thrush: The usual adult dose is 4 to 6 ml (400,000 to 600,000 units) of nilstat drops, swished in the mouth and swallowed four times daily after meals and at bedtime. For infants and children, the dosage is usually based on their weight and age.
  • Intestinal candidiasis: The usual adult dose is 4 to 6 ml (400,000 to 600,000 units) of nilstat drops, three times daily before meals. For infants and children, the dosage is usually based on their weight and age.
  • Prevention of fungal infections: The usual adult dose is 4 to 6 ml (400,000 to 600,000 units) of nilstat drops, twice daily. For infants and children, the dosage is usually based on their weight and age.

Storage

Nilstat drops, also known as nystatin drops, should be stored at room temperature, between 15°c to 30°c (59°f to 86°f). The medication must be retain away from straight sunlight, heat, and wetness. It is important to keep the medication in the original container with the cap tightly closed.


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