Introduction
Nospa
contains the active ingredient drotaverine, which is an antispasmodic agent
that works by relaxing the smooth muscles in the walls of blood vessels and
organs in the body.
Drotaverine acts by inhibiting the enzyme phosphodiesterase-4 (pde-4) and promoting the accumulation of cyclic amp, a molecule that regulates the contraction and relaxation of smooth muscles. By doing so, drotaverine can relieve spasm and pain in the gastrointestinal tract, biliary tract, uterus, and other organs.
Uses of nospa tablet
Some of the conditions for which nospa tablet is commonly prescribed include:
- Irritable
bowel syndrome (ibs): nospa tablet can help relieve the abdominal pain, bloating,
and cramping associated with ibs.
- Dysmenorrhea
(painful menstrual cramps): nospa tablet can reduce the intensity and duration
of menstrual cramps and may also help alleviate other symptoms of dysmenorrhea
such as headaches, back pain, and nausea.
- Cholecystitis: nospa tablet can help relieve the abdominal pain associated with inflammation of the gallbladder.
- Renal colic: nospa tablet can help relieve the intense pain caused by the passage of kidney stones.
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Drug
interactions
Some of the
drugs that may interact with nospa tablet,
- Cimetidine:
cimetidine may increase the concentration of drotaverine in the blood, which
can increase the risk of side effects.
- Ketoconazole:
ketoconazole may inhibit the metabolism of drotaverine, which can increase the
concentration of the drug in the blood and increase the risk of side effects.
- Rifampicin:
rifampicin may increase the metabolism of drotaverine, which can reduce its
effectiveness.
- Other
antispasmodic drugs: taking nospa tablet with other antispasmodic drugs can
increase the risk of side effects.
- Alcohol:
drinking alcohol while taking nospa tablet can increase the risk of drowsiness
and dizziness.
Disease interactions
Some of the
diseases or medical conditions that may interact with nospa tablet,
- Liver or
kidney disease: nospa tablet is primarily metabolized by the liver and excreted
by the kidneys, so patients with liver or kidney disease may be at increased
risk of side effects.
- Heart disease:
nospa tablet may cause changes in heart rate or rhythm, so patients with heart
disease should use caution when taking this medication.
- Low blood
pressure: nospa tablet may cause a drop in blood pressure, so patients with low
blood pressure should use caution when taking this medication.
- Glaucoma:
nospa tablet may cause an increase in eye pressure, so patients with glaucoma
should use caution when taking this medication.
- Myasthenia
gravis: nospa tablet may worsen symptoms of myasthenia gravis, a neuromuscular
disorder that causes muscle weakness.
Food interactions
There are no known food interactions associated with nospa tablet.
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Side effects of nospa tablet
The most
usual side effects of nospa tablet include:
- Nausea
- Vomiting
- Headache
- Dizziness
- Dry mouth
- Diarrhea
- Abdominal
pain
- Fatigue
- Sweating
- Rash
Dosage form
- The dosage
form of nospa tablet is oral tablets. These tablets are formulated to be taken
orally (by mouth) with a glass of water. They are typically small, round, and
may be scored or imprinted with the name or logo of the manufacturer.
- Nospa
tablets are available in different strengths, such as 40mg, 80mg or others,
depending on the country or region where it is marketed. The strength of the
tablet determines the amount of drotaverine hydrochloride present in each
tablet.
Dosing information
The recommended dose of nospa tablet for adults is usually 40-80 mg taken orally 3-4 times per day. The maximum daily dose is usually not more than 240 mg.
Packaging
Nospa
tablets containing drotaverine hydrochloride may be packaged in a blister pack
or a bottle.
- Blister packs
are individual compartments made of plastic or aluminum foil that hold a single
tablet each. This type of packaging is commonly used for medications that need
to be taken in specific doses, such as daily or weekly.
- Bottles, on
the other hand, may contain multiple tablets and are usually made of plastic or
glass with a child-resistant cap. This type of packaging is commonly used for
medications that are taken on an as-needed basis.
Storage
Here are
some general guidelines:
- Store the
tablets in a cool, dry place away from direct sunlight, heat, and moisture. The
ideal storage temperature is usually between 15°c and 30°c.
- Keep the
tablets in their original packaging until you are ready to use them. This will
assist safeguard them from light and wetness.
- Keep the
tablets out of reach of children and pets to prevent accidental ingestion.
- Do not store
nospa tablets in the bathroom or any other damp or humid area, as this can
increase the risk of moisture damage.
- Check the
expiration date on the packaging before taking the tablets. Do not utilize them
if they are over their termination date.
