Do you know what is nuberol forte?

Nuberol forte is the product of searle pharma, nuberol forte contains paracetamol bp & orphenadrine citrate bp as an active substance, it is mainly considered an analgesic muscle relaxant.


Acetaminophen usually referred to as paracetamol, is a drug used to treat mild to moderate pain and fever. Paracetamol's pharmacological similarities to traditional nonsteroidal anti-inflammatory medications (nsaids), which work by inhibiting cox-1 and cox 2 enzymes and are particularly comparable to selective cox-2 inhibitors, by decreasing the active form of the cox-1 and cox-2 enzymes, paracetamol prevents the production of prostaglandins. Only when arachidonic acid and peroxide levels are low does this happen. This explains why paracetamol appears to have a cox-2 selectivity as cox-2 is the main type of cyclooxygenase under these circumstances.


Orphenadrine considered an adjuvant for the symptomatic alleviation of musculoskeletal pain and discomfort is the muscarinic antagonist. The muscarinic antagonist is a medication recommended for the treatment of discomfort brought on by acute painful musculoskeletal problems as a supplement to rest, physical therapy, and other therapies. Anticholinergic orphenadrine has a primarily central action and a meager peripheral effect.


Additionally, it has some local anesthetic and weak antihistaminic effects. The result of an imbalance between cholinergic and dopaminergic neurotransmission in the basal ganglia brought on by a drop in dopamine is parkinson's syndrome. Orphenadrine improves the rigidity and tremor of parkinson's disease and parkinsonian syndromes by restoring the physiological balance. Bradykinesia is affected less severely.


The high concentration of peroxides presents in inflammatory circumstances 

Negates the lowering effects of paracetamol. As a result, paracetamol's anti-inflammatory effect is minimal.

 

Uses of nuberol forte

Following symptoms, diseases or conditions can be controlled, improved, or treated by orphenadrine citrate / paracetamol.

  • Headache
  • Fever
  • Flu
  • Cold
  • Periods pain
  • Ear pain
  • Toothache
  • Joint pain
  • Acute painful musculoskeletal condition

Daily intake of nuberol forte

it is generally recommended twice or thrice a day.


As it is prescribed medicine, do not self-medicate!


A nuberol forte pill should be taken with a glass of water. Take a full breath of it. Follow the doctor's advice on dose and frequency. Changes to the dosage or frequency should not be made because they may result in new problems. Ideally taken with food. You can also take it without a meal, though.


Additionally, since it does not induce either condition, it is a safe alternative to other painkillers if you have gastritis.


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Dosage, strengths, pack size & price in the market?

Nuberol forte is available in the strength of 650/50mg i-e paracetamol & orphenadrine citrate respectively.


Pack size of 15 tablets available in the market with the mrp of 106.47 rupees.


Side effects of nuberol forte

There might be some side effects that can occur due to orphenadrine citrate / paracetamol.

  • Blurred vision
  • Dry mouth
  • Palpitation
  • Tachycardia

 Alternative brands available in pakistan market:

  • Sinaxamol
  • Norflex

Risk & warnings

A contraindication is a hypersensitivity to paracetamol or orphenadrine citrate. 

Additionally, you should avoid using orphenadrine citrate/paracetamol if you have 

Any of the following conditions:

  • Hepatic dysfunction
  • Hypersensitivity
  • Cardio-spasm
  • Glaucoma
  • Hypersensitivity
  • Myasthenic fibrosis
  • Prostate enlargement
  • Blockage in the duodenum or pylorus
  • Peptic ulcers stenosing

Precautions

Inform your doctor about all of your current prescriptions, over-the-counter goods (such as vitamins, herbal supplements, etc.), allergies, existing medical conditions, and pre-existing disorders before using orphenadrine citrate/paracetamol (e.g., pregnancy, upcoming surgery, etc.). You can be more susceptible to the drug's side effects if you have certain medical conditions.


Follow your doctor's instructions or the instructions on the package insert when taking. Your condition will determine your dosage. If your issue persists or gets worse, let your doctor know. The following list of key counselling points is provided.


If you are allergic to paracetamol, avoid using it.


If you often consume alcoholic beverages, avoid using paracetamol.


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Drug interactions


The effects of orphenadrine citrate and paracetamol may alter if you take other 

Medications or over-the-counter items at the same time. This could make your medication less effective or put you at greater risk of side

Effects. 


Inform your doctor of all the medications, vitamins, and herbal supplements you

Use so they can assist you in avoiding or managing drug interactions. 

The following medicines and items may interact with orphenadrine 

Citrate/paracetamol:

  • Ketoconazole
  • Leflunomide
  • Prilocaine
  • Teriflunomide
  • Juxtapid mipomersen
  • Alcohol
  • Disrupt some laboratory tests

You can easily buy online medicine In Pakistan and get it delivered to your doorstep with InstaCare. Visit the website or call at 03171777509 for further information.


Source: https://instacare.pk/blog/nuberol-forte-uses-side-effects-and-price-in-pakistan