Onset Tablet - Uses Side Effects And Price In Pakistan

Onset Tablet is an antiemetic medication used to treat and prevent nausea and vomiting caused by various medical conditions, such as stomach upset and post-surgery complications. It is available in a tablet form and should be taken as directed by a doctor or pharmacist.

By InstaCare

Apr 13 2023

Medicines

Drugs and Medications

Picture of Onset Tablet - Uses Side Effects And Price In Pakistan

Introduction

Onset is a medication that contains the active ingredient ondansetron. Ondansetron is a type of medication called a selective serotonin receptor antagonist, which effort by choke the work of serotonin in the body.

Uses of onset tablet

Onset can be used for the following purposes:

Chemotherapy-induced nausea and vomiting: onset can help prevent and treat nausea and vomiting caused by chemotherapy.
Radiation therapy-induced nausea and vomiting: onset may be used to prevent and treat nausea and vomiting caused by radiation therapy.
Post-operative nausea and vomiting: onset can be used to prevent and treat nausea and vomiting after surgery.
Gastroenteritis-induced nausea and vomiting
Morning sickness: onset can also be used to treat nausea and vomiting during pregnancy.

Drug interactions

Some examples of drugs that may interact with onset include:

Apomorphine: concurrent use of onset and apomorphine may cause low blood pressure and loss of consciousness.
Tramadol: onset may reduce the effectiveness of tramadol.
Carbamazepine: onset may increase the levels of carbamazepine in the blood, which can lead to adverse effects.
Rifampin: onset may decrease the effectiveness of rifampin.
Phenobarbital: onset may reduce the effectiveness of phenobarbital.
Serotonin reuptake inhibitors (ssris): concurrent use of onset and ssris may increase the risk of serotonin syndrome, which is a potentially life-threatening condition characterized by fever, agitation, confusion, and muscle rigidity.

Disease interactions

Some examples of medical conditions that may interact with onset include:

Liver disease: onset is primarily metabolized by the liver, and its clearance may be impaired in patients with liver disease. A lower dose of onset may be required in patients with liver disease.
Congenital long qt syndrome: onset may increase the risk of arrhythmias in patients with congenital long qt syndrome.
Intestinal obstruction: onset may mask the symptoms of intestinal obstruction, which can lead to delayed diagnosis and treatment.
Electrolyte imbalances: onset may cause electrolyte imbalances, such as hypokalemia and hypomagnesemia, which can worsen certain medical conditions.
Hypersensitivity: onset should be used with caution in patients with a history of hypersensitivity to ondansetron or other selective serotonin receptor antagonists.

Food interactions

Alcohol consumption may worsen the side effects of onset, such as dizziness and drowsiness. It is recommended to avoid alcohol while taking onset or to limit alcohol intake.

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Side effects of onset tablet

Some common side effects of onset include:

Headache
Constipation
Diarrhea
Dizziness
Drowsiness
Fatigue
Flushing
Fever
Muscle spasms

In rare cases, onset may cause more serious side effects, such as:

Allergic reactions, including anaphylaxis
Qt prolongation (a heart rhythm disorder)
Serotonin syndrome (a potentially life-threatening condition characterized by fever, agitation, confusion, and muscle rigidity)

Dosage forms

Onset, contains ondansetron, is available in various dosage forms,

Tablets: onset tablets are available in strengths of 4 mg and 8 mg. They are typically taken orally, with or without food, as directed by the healthcare provider.
Orally disintegrating tablets (odt): onset odts are available in strengths of 4 mg and 8 mg. They are designed to dissolve quickly in the mouth without the need for water.
Injection: onset injection is available in vials containing 2 mg/ml, 4 mg/ml, and 8 mg/4 ml of ondansetron. It is typically administered by healthcare professionals as an intravenous injection.
Oral solution: onset oral solution is available in a 4 mg/ml concentration

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Dosing information

The following dosing information is a general guideline:

For prevention of nausea and vomiting caused by chemotherapy: the recommended adult dose is 8 mg of onset taken orally 30 minutes before chemotherapy. This dose may be repeated every 8 hours for up to 2 days after chemotherapy. Alternatively, the healthcare provider may prescribe a single dose of 24 mg of onset orally.
For prevention of nausea and vomiting caused by radiation therapy: the recommended adult dose is 8 mg of onset taken orally 1 to 2 hours before radiation therapy. This dose may be repeated every 8 hours for 1 to 2 days after radiation therapy.
For prevention of postoperative nausea and vomiting: the recommended adult dose is 16 mg of onset taken orally 1 hour before anesthesia induction. This dose may be repeated every 8 hours for up to 24 hours after surgery.
For treatment of nausea and vomiting: the recommended adult dose is 8 mg of onset taken orally every 8 hours as needed. Alternatively, the healthcare provider may prescribe a single dose of 16 mg of onset orally.
For pediatric patients: the dosing information for pediatric patients may vary depending on the patient's age and weight.

Packaging

Some examples of the packaging of onset,

Tablets: onset tablets are typically packaged in blister packs or bottles. The blister packs may contain 10 or 30 tablets, while the bottles may contain 30 or 100 tablets.
Orally disintegrating tablets (odt): onset odts are typically packaged in blister packs or bottles. The blister packs may contain 10 or 30 tablets, while the bottles may contain 30 or 100 tablets.
Injection: onset injection is typically packaged in vials containing 2 mg/ml, 4 mg/ml, and 8 mg/4 ml of ondansetron. The vials may be packaged individually or in multi-dose vials.
Oral solution: onset oral solution is typically packaged in bottles containing 50 ml or 100 ml of solution.

Storage

General guidelines for storing onset:

Tablets and orally disintegrating tablets (odt): onset tablets and odts should be stored at room temperature, between 20°c to 25°c (68°f to 77°f), in a dry place. Avoid revealing them to wetness, heat, or straight sunlight.
Injection: onset injection should be stored at room temperature, between 20°c to 25°c (68°f to 77°f), in a dry place. Do not freeze the injection, and protect it from light.
Oral solution: onset oral solution should be stored at room temperature, between 20°c to 25°c (68°f to 77°f), in a dry place. It should be protected from light and kept in the original container.

You can easily buy online medicine In Pakistan and get it delivered to your doorstep with InstaCare. Visit the website or call at 03171777509 for further information.

Source: https://instacare.pk/blog/onset-tablet-uses-side-effects-and-price-in-pakistan

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Frequently Asked Questions

What is onset Tablet used for?

Onset is a brand name for a medication called acetaminophen (also known as paracetamol). It is a common pain reliever and fever reducer that is used to treat mild to moderate pain, including headaches, muscle aches, menstrual cramps, and toothaches. It is also commonly used to reduce fever associated with colds, flu, or other viral infections. Acetaminophen works by blocking the production of prostaglandins, which are chemicals in the body that cause pain and inflammation. It is generally considered safe and effective when used as directed, although it may cause side effects in some people, particularly if taken in high doses or for extended periods of time. Onset tablets are typically taken orally, with or without food, as directed by a healthcare provider. It is important to follow the instructions on the label carefully and to avoid taking more than the recommended dose or taking the medication for longer than recommended, as this can increase the risk of side effects. If you experience any side effects or have any concerns about the use of Onset or acetaminophen, it is important to consult with a healthcare provider.

Does onset Tablet make you sleep?

Onset tablets contain acetaminophen, which is a pain reliever and fever reducer. Acetaminophen is not typically known to cause drowsiness or sedation as a side effect. However, if you are taking a medication that contains acetaminophen in combination with other drugs, such as a sleep aid or muscle relaxant, those drugs may cause drowsiness or other side effects. It is important to always read the label and instructions carefully before taking any medication, and to talk to your healthcare provider or pharmacist if you have any questions or concerns about the potential side effects. If you experience any unexpected or concerning side effects while taking Onset or any other medication, it is important to contact a healthcare provider right away.

What are the side effects of of onset tablets?

Onset tablets contain acetaminophen, which is a pain reliever and fever reducer. When used as directed, acetaminophen is generally considered safe and well-tolerated by most people. However, like all medications, Onset tablets can cause side effects in some people. The most common side effects of acetaminophen include: Nausea and vomiting Upset stomach or abdominal pain Headache Dizziness or lightheadedness Skin rash or hives More serious side effects are rare, but can include: Liver damage (particularly in people who take high doses or use acetaminophen for long periods of time) Allergic reactions, including swelling of the face, tongue, or throat, and difficulty breathing Low platelet count, which can increase the risk of bleeding If you experience any of these side effects or have concerns about the use of Onset or acetaminophen, it is important to contact a healthcare provider right away. It is also important to follow the instructions on the label carefully and to avoid taking more than the recommended dose or taking the medication for longer than recommended, as this can increase the risk of side effects.

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