Hey, let’s discuss about oxidil injection, what is oxidil? What are the uses of oxidil and what are their side effects and much more. So, let’s start!
Introduction
The generic name of oxidil injection is ceftriaxone injection, and it belongs to drug class which is 3rd generation cephalosporins.
Uses of oxidil injection
There are some uses of oxidil injection are given below,
- E-coli
- Pneumonia
- Meningitis
- Oxidil injection also prevent some infections in patients who recently suffered from any type of surgery.
Drug interactions
There are some drugs which are not good if we taking them with oxidil injection, the list of drugs is given below,
- Bcg vaccine
- Calcium chloride
- Calcium gluceptate
- Calcium gluconate
- Cholera vaccine, live
- Edetate calcium di-sodium
- Intravenous electrolyte solution
- Leucovorin
- Levoleucovorin
- Parenteral nutrition solution with electrolytes
- Pentetate calcium tri-sodium
- Typhoid vaccine, live
- Fluconazole
- Vancomycin
Disease interactions
There are some drugs in which oxidil injection is not good to inject and cause some harmful effectsColitis
- Hyperbilirubinemia
- Gall bladder disease
- Pancreatitis
- Prothrombin time alterations
- Renal disease
- Liver disease
- Seizures disorders
- Diabetes
- Bleeding problems
Food interactions
There are no reported food interactions of ceftriaxone (oxidil injection).
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Side effects of oxidil injection
Every drug has good or bad effect, the list of side effects of oxidil injection is given below:
Serious side effects
- Severe stomach pain
- Diarrhea
- Fever
- Chills
- Sweating
- Nausea and vomiting
- Pain in upper stomach
- Pale skin
- Dark colored urine
- Breathing problems
- Blood cell disorder
- Headache
- Chest pain
- Dizziness
- Weakness
- Tingling or numbness
- Kidney problems
Common side effects
- Diarrhea
- Vaginal discharge
- Vaginal itching
- Blood cell disorder
- Rashes
- Abnormal liver function test
- Hard lump on injection site
- Warmth and tight feeling on injection site
Precautions & warnings
- Never take oxidil injection if you are allergic to cefazolin or cephalosporin antibiotics.
- Never use oxidil injection (ceftriaxone) in children’s
- Never use oxidil injection (ceftriaxone) if you are suffering from any liver disease
- Never use oxidil injection (ceftriaxone) if you are suffering from kidney problems
- Never use oxidil injection (ceftriaxone) if you are suffering from gall bladder disease
- Never use oxidil injection (ceftriaxone) if you are suffering from diabetes
- Never use oxidil injection (ceftriaxone) if you are suffering from bleeding problems
- Always consult your doctor or pharmacist during pregnancy while taking ceftriaxone
- Always consult your doctor or pharmacist during breast-feeding while taking ceftriaxone
- Never mix ceftriaxone with another antibiotics
Dosage forms
Injectable powder for injection
- 1g
- 10g
- 2g
- 250mg
- 500mg
Intravenous solution
- 1g/50ml
- 2g/50ml
Dosing
For adults
Bronchitis
1-2g one time in a day for 4-14 days
Bacteremia
1-2g one time in a day for 4-14 days
Joint infection
1-2g one time in a day for 4-14 days
Osteomyelitis
1-2g one time in a day for 4-14 days
Pneumonia
1-2g one time in a day for 4-14 days
Septicemia
1-2g one time in a day for 4-14 days
Bacterial infection
1-2g one time in a day for 4-14 days
Urinary tract infection
1-2g one time in a day for 4-14 days
Gonococcal infections
250mg intramuscular one time in a day
Intra-abdominal infection
1-2g one time in a day for 4-14 days
Meningitis
1-2g one time in a day for 4-14 days
Pelvic inflammatory disease
1-2g one time in a day for 4-14 days
Soft tissue infections
1-2g one time in a day for 4-14 days
Surgical prophylaxis
1g iv 30-120 min before surgery
Chancroid
250mg im one time in a day
Conjunctivitis
1g im one time in a day
Bacterial endocarditis prophylaxis
1g iv 30-60 min before dental surgery
Epididymitis sexually transmitted
250mg im once a day
Gonococcal infection disseminated
Arthritis dermatitis syndrome
1g every 12hr
Gonococcal endocarditis and meningitis
1-2g every 12-24hr
Lyme disease-arthritis
1-2g one time in a day for 4-14 days
Lyme disease carditis
2g once a day for 14-21 days
Lyme disease – neurological
2g once a day for 14-21 days
Meningococcal meningitis prophylaxis
250mg im one time in a day
Neurosyphilis
2g once a day for 10-14 days
Proctitis
Patient less than 150kg
500mg im once a day
Patient at-least 150kg
1g im once a day
Std prophylaxis
250mg im once a day
Syphilis-early
1g one time in a day for 10-14 days
For pediatrics
Bronchitis
2g once a day
Bacteremia
2g once a day
Joint infection
2g once a day
Osteomyelitis
2g once a day
Pneumonia
2g once a day
Septicemia
2g once a day
Bacterial infection
2g once a day
Urinary tract infection
2g once a day
Gonococcal infections
25-50mg per dose once a day
Intra-abdominal infection
2g once a day
Meningitis
4g once a day
Soft tissue infections
2g once a day
Surgical prophylaxis
2g once a day
Chancroid
50mg once a day
Conjunctivitis
1g once a day
Bacterial endocarditis prophylaxis
1g once a day
Gonococcal infection disseminated
20-50mg every 24hr
Lyme disease
2g once a day
Meningococcal meningitis prophylaxis
Patient less than 15 year
125mg once a day
Patient greater than 15year
250mg once a day
Std prophylaxis
250mg once a day
Endocarditis
4g once a day
Otitis
1g once a day
Salmonella enteric fever
1g once a day
Salmonella gastroenteritis
1g once a day
Ocular infection
25-50mg once a day
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Price of oxidil injection
- Oxidil 1g iv injection is of 385pkr
- Oxidil 500mg iv is of 245pkr
- Oxidil 250mg im is of 185pkr
- Oxidil 250mg iv is of 150pkr
- Oxidil 500mg im is of 220pkr
Packaging
Oxidil injections are packaged in vials.
You can easily buy online medicine In Pakistan and get it delivered to your doorstep with InstaCare. Visit the website or call at 0317-1777509 for further information.
Source: https://instacare.pk/blog/oxidil-injection-uses-side-effects-and-price-in-pakistan