Rancard XR 1000mg is the first prescribed drug. It is a
special kind of medicine with an extended-release form in which the active
substance dissolves in the body to release the dose throughout the day. Mainly
employed in the treatment of type 2 diabetes, it proved pretty helpful in
managing high blood sugar levels. This medication is essential for
survival-dependent people who ought to know the workings of this medicine and
the various pros, cons, and precautionary measures to be taken when applying
it.
What is Rancard XR 1000mg?
Rancard XR 1000mg falls under the biguanide class of medicines; this is one type of oral anti-diabetic medicine. Metformin hydrochloride, the active ingredient of this drug, increases insulin sensitivity and decreases glucose production in the liver, hence lowering blood sugar levels in the body. The "XR" in Rancard XR stands for "extended release," which means this drug has inherent properties that ensure it is released gradually throughout the day to exert a constant effect on blood sugar throughout the day.
Mechanism of Action
Rancard XR 1000mg plays an intense role in managing type 2
diabetes through insulin resistance and excess glucose output suppression by
the liver.
Increased Insulin Sensitivity
Rancard XR makes the
cellular body cells more sensitive to insulin, increases glucose absorption
from the circulation of blood into cells, and decreases general blood sugar
concentration.
Reduced Glucose Production
Glucose is reduced in its production by the liver, which in the long run decreases blood sugar levels.
Rancard XR shall be operated under two principals to ensure
blood sugar remains at a healthy tolerable level. The complications of diabetes
that concern heart diseases, diseases caused by nerve damages, and those
concerning eyes are what is particularly in need of quelling reduction.
Recommended Dosage and How to Take
In essence, many factors will come into play in determining
the dosage of Rancard XR 1000mg, including organism reactions and blood sugar
tolerance. The usual recommended
starting dose is 500 mg once daily; the maximum recommended dosage of 1000 mg
and over in a case when it is necessary according to further assessment.
Rancard XR 1000 mg caplets are supplied as white, oblong, biconvex, sustained
release caplets containing 1000 mg of metformin HCl debossed on one side and
plain on the other the caplets are in bottles of 140s and 1000s.
- Dosage: Taken orally, once daily, taken with an evening meal. Food helps to decrease gastrointestinal side effects which is the most common side effect caused by metformin ingestion.
- If Mistaken Missed Time: If you miss a dose, then take it the moment you remember.
View More: CaC 1000 - Uses Side Effects And Price In Pakistan
Benefits of Rancard XR 1000 mg
Rancard XR has some associated benefits with the long-term
management of T2D treatment, including but not limited to the following:
- Rancard XR has a very strong association with the reduction
of blood glucose near normal and the maintenance of that target level; quite
important in preventing complications of chronic diabetes.
- In contrast to many other antidiabetic drugs, Rancard XR
does not contribute to weight increase; indeed, it may have some benefit in
weight loss or maintenance at best weight levels for the management of
diabetes.
- An extended-release formulation increases its patient
convenience and compliance with the ease of its once-daily regimen.
- Several studies associate metformin, the active ingredient
in Rancard XR, or the brand Rancard XR itself with cardiovascular benefit and
with providing some protection against heart disease in subjects with type 2
diabetes.
Adverse Effects
As with other drugs, Rancard XR 1000mg is likely to have
some side effects but not all may have them. Among the common side effects, a
majority are of gastrointestinal originality, and in most of the cases, this
annoyance passes as a person's organism habituates to the drug.
Common Side Effects:
- Nausea
- Vomiting
- Diarrhea
- Stomach Upset
Serious Side Effects are rare, but Rancard XR can also cause the following serious side effects:
- A severe yet possibly fatal adverse reaction resulting from the elevation of lactic acid levels in the body. Common signs and symptoms include muscle pain, weakness, breathing difficulties, and fatigue. If this happens, a patient cannot seek medical help.
- Metformin has been reported to interfere with the absorption
of vitamin B12 in the long run, so its deficiency could be expected. Therefore,
serum vitamin B12 levels should be estimated in patients with long-term use of
metformin.
Precautions and Warnings
Before taking Rancard XR 1000mg, people should consult their
doctor about all the relevant facts about their health.
Renal Impairment
Some of the properties of Metformin include that they are
eliminated through the kidneys. Therefore, Rancard XR cannot be used for
patients with severely compromised renal function. Renal impairment raises the
problem of large amounts of drugs that can lead to high systemic
concentrations, leading to severe or even fatal complications.
Hepatic Impairment
Another Absolute Contradiction is hepatotoxicity because the
risk of lactic acidosis is an extremely high possibility in patients with
hepatic disease; thus, Rancard XR should be used very carefully in patients
with known hepatic disease.
Pregnancy and Lactation
Pregnant or breastfeeding women should not take Rancard XR
unless the doctor feels that it is necessary. Without a doubt, the drug is to
be avoided absolutely in both the cases mentioned above.
Alcohol
Avoid administering
Rancard XR with large amounts of alcohol, which definitely will increase the
risk of lactic acidosis.
Drug Interactions
Rancard XR can interact with other drugs to change its
effectiveness or increase side effects. Here are some very significant
interactions:
Diuretics and Blood Pressure Meds
Co-administration of Rancard XR with some diuretics and
blood pressure medicines increases the risk of lactic acidosis.
Steroids
Steroids decrease the drug's efficiency by elevating blood
sugar levels.
Contrast Agents
Patients must be advised to discontinue Rancard XR during or
a few days before the examination process as contrast reagents may add to the
negative impact of renal impairment, leading to the risk of lactic acidosis.
Patients should be informed that they must notify the
prescribing health care provider of all prescription and nonprescription
medications, supplements, or herbal preparations they are currently taking
before initiating Rancard XR.
When to seek medical help
Patients should inform their doctor if they experience any unusual symptoms, or if blood glucose control deteriorates during administration of Rancard XR as prescribed Patients should be counselled for the: Patient to inform the health care provider immediately if the patient experiences the following:
- Muscle pain, respiratory distress, abdominal pain, or
dizziness.
- Nausea, vomiting and diarrhea that persist.
- Onset of rash, itching, swelling, or shortness of breath for
which no previous reason was identified.
- This includes symptoms of B 12 avitaminosis asthenia,
dyspnoea, or paraesthesia of limbs.
Conclusion
It concludes that Rancard XR 1000 mg is a very useful drug in the treatment of type 2 diabetes, as, in addition to effective blood glucose control, it can add the plus of once-daily dosing; however, as for every drug, patients should be warned against risks and possible side effects.
If the patients undergo the changes in lifestyle that are
needed, follow the advice of the treating healthcare professional and have
regular follow-ups, they will be able to manage their diabetes appropriately
and reduce as much as possible the risk of complications.
Please book an appointment with the Best Diabetologist in Lahore, Karachi, Islamabad, and all major cities of Pakistan through InstaCare, or call our helpline at 03171777509 to find a verified doctor for your disease.