Have you ever heard about beta-lactamase inhibitors? Because this drug is belonged to class which is called beta-lactamase inhibitors. Don’t worry I am here to gives you details about this medication.


Beta-Lactamase Inhibitors


Actually beta-lactamase are class of enzymes that are produced by bacteria that break and open the beta-lactam ring and inactive the beta-lactam antibiotic.


Introduction


The generic name of Augmentin is Amoxicillin and clavulanate potassium. Amoxicillin is penicillin antibiotic that fights with bacteria in your human body and clavulanate potassium is beta-lactamase inhibitors that helps in prevention of certain bacteria from becoming resistant to amoxicillin.


Uses of Augmentin Tablet


Augmentin Tablet antibiotic is used in different medical conditions which are given below,

  • Pneumonia (Inflammation of air sacs of lungs)
  • Ear infections
  • Bronchitis (Inflammation of bronchi of lungs)
  • Urinary tract infections (UTI)
  • Skin infections

Interactions

There are some drugs which are interact with Augmentin medicine are given below,

  • Bcg vaccine
  • Cholera vaccine, live
  • Leflunomide
  • Levoketoconazole
  • Lomitapide
  • Methotrexate
  • Mipomersen
  • Pexidartinib
  • Teriflunomide
  • Typhoid vaccine, live
  • Warfarin
  • Thioguanine
  • Tetracycline
  • Trabectedin
  • Sodium iodide i-123
  • Sarecycline
  • Sodium iodide i-131
  • Oxytetracycline
  • Pegaspargase
  • Pemetrexed
  • Peginterferon beta-1a
  • Remdesivir
  • Anisindione
  • Asparaginase erwinia chrysanthemi
  • Balsalazide
  • Bedaquiline
  • Bifidobacterium infantis
  • Black cohosh
  • Brentuximab
  • Calaspargase pegol
  • Clofarabine
  • Cannabidiol
  • Daclizumab
  • Demeclocycline
  • Dicumarol
  • Doxycycline
  • Efavirenz
  • Entecavir
  • Estradiol
  • Ethinyl estradiol
  • Guar gum
  • Idelalisib
  • Interferon beta-1a
  • Interferon beta-1b
  • Naltrexone
  • Allopurinol
  • Probenecid

Food Interactions

Avoid taking this medication together or after eating a high-fat meal which contains lots of fatty acids in it because it makes absorption of medicine harder.


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Side Effects of Augmentin Tablet


Everything which has effect have side effects too. This medication has also some side effects, if you are suffering from any side effects while using the medication, please consult your pharmacist or health care provider as soon as possible. Side effects are given below,

  • Severe stomach pain
  • Diarrhea
  • Loss of appetite
  • Little or no urination
  • Pale yellow skin color
  • Bleeding
  • Nausea
  • Vomiting
  • Rash
  • Itching
  • Vaginal discharge
  • Vaginal itching
  • Diaper rash

Dosage Forms And Strengths Of Augmentin

There are some dosage forms of Augmentin are given below,


1- Tablets

  • 250mg/125mg
  • 500mg/125mg
  • 875mg/125mg

2- Chewable tablets

  • 125mg/31.25mg
  • 200mg/28.5mg
  • 250mg/62.5mg
  • 400mg/57mg

3- Powder for oral suspension

  • 125mg/31.25mg per 5ml
  • 200mg/28.5mg per 5ml
  • 250mg/62.5mg per 5ml
  • 400mg/57mg per 5ml

Dosage Of Augmentin Tablet

Augmentin medicine gives best effect when you take it in start of your meal.


Adults (Augmentin Tablet)

  • The usual dose of 500mg tablet of Augmentin is for every 12 hours.
  • The usual dose of 250mg tablet of Augmentin is for every 8 hours.
  • For severe infections 875mg tablet of Augmentin is for every 12 hours.
  • For severe infections 500mg tablet of Augmentin is for every 8 hours.

Adults (Augmentin oral suspension)

Many adults have difficulty in swallowing tablet that’s why their health care provider gives them oral suspension of Augmentin.

  • 125mg/5ml or 250mg/5ml suspension is given to adult patients in place of 500 mg tablet.
  • 200mg/5ml or 400mg/5ml suspension is given to adult patients in place of 875mg tablet.

Pediatric Patients

Neonates and infants age less than 12 weeks (less than 3 months)

  • The dose of Augmentin 30mg/kg/day is for every 12hours.
  • The dose of Augmentin 200mg/5ml is recommended for some limited age group, In this case you should consult your doctor or pharmacist first.

Patient aged 12 weeks or older (Augmentin oral suspension)

  • 200mg/5ml and 400mg/5ml oral suspension is for every 12 hours

Patient aged 12 weeks or older (Augmentin Tablet)

  • 200mg and 400mg chewable tablets of Augmentin is given only in those children’s which are not phenylketonurics.

The 250mg tablet of Augmentin is not used in child weigh at least 40kg due to different ratios of ingredients present in Augmentin which are amoxicillin and clavulanate potassium.


Precautions


There are some medical conditions in which Augmentin is strictly prohibited are given below,

  • Please don’t use Augmentin if you are allergic to amoxicillin and clavulanate potassium
  • If you have severe kidney disease
  • If you had liver problems
  • If you are hypersensitive to penicillin’s or cephalosporins antibiotics  
  • If you had mononucleosis
  • If you have phenylketonuria (PKU)
  • If you are breast-feeding a baby
  • Augmentin make birth control pills less effective so, if you are taking birth control pills ask your doctor or pharmacist first before taking Augmentin medication.
  • Do not give child this medication without medical advice.
  • Always shake your Augmentin suspension before use.
  • Do not crush Augmentin tablet before use, Swallow the pill whole or half but don’t crush the tablet of Augmentin.
  • Augmentin will not treat viral infections such as common cold caused by viruses, it only treats bacterial infections.

Packaging

Augmentin medicine is packaged in Strips and Bottles and vials and dropper bottles.

Price

  • Augmentin 1gm/200mg vial is of 180 Pkr
  • Augmentin 457mg suspension is of 176 Pkr
  • Augmentin 375mg tablet is of 220 Pkr
  • Augmentin 156.25mg suspension is of 192 Pkr
  • Augmentin 62.5mg suspension is of 183 Pkr
  • Augmentin BD 400mg suspension is of 331 Pkr
  • Augmentin 625mg tablet is of 229 Pkr
  • Augmentin D S 312.50mg/312.5mg suspension is of 313 Pkr
  • Augmentin BD 1000mg/1gm tablet is of 278 Pkr

You can easily buy online medicine In Pakistan and get it delivered to your doorstep with InstaCare. Visit the website or call at 0317-1777509 for further information.


Source: https://instacare.pk/blog/augmentin-tablet-uses-dosage-price-in-pakistan