Metodine-Df Tablet - Uses Side Effects And Price In Pakistan

Metodine-Df is an antimicrobial tablet used to treat bacterial and protozoal infections such as diarrhea and dysentery. It contains Diloxanide and Metronidazole, which work together to fight infections. This medication should only be used as advised by a doctor, stored at room temperature away from direct heat and sunlight, and kept out of reach of children and pets.

By InstaCare

Apr 12 2023

Medicines

Drugs and Medications

Picture of Metodine-Df Tablet - Uses Side Effects And Price In Pakistan

Introduction

Metodine df is a combination tablet that contains two active ingredients: diloxanide and metronidazole. Diloxanide is an anti-protozoal drug that works by killing and preventing the growth of certain types of protozoal organisms, particularly entamoeba histolytica, which causes amoebic dysentery. Metronidazole is an antibiotic that is effective against certain types of bacteria and protozoa, including those that cause infections of the gastrointestinal tract.

The combination of these two drugs in metodine df makes it effective against a wide range of protozoal and bacterial infections of the digestive system, such as amoebic dysentery, giardiasis, and bacterial infections of the intestine. It is available in tablet form and is usually taken orally with a glass of water.

Uses of metodine-df tablet

Metodine-df is primarily used to treat a variety of gastrointestinal infections, including:

Amoebic dysentery: it is a parasitic infection caused by entamoeba histolytica that affects the large intestine and can cause severe diarrhea, abdominal pain, and fever.
Giardiasis: it is an infection caused by a microscopic parasite called giardia lamblia that can cause diarrhea, abdominal cramps, and bloating.
Bacterial infections of the intestine: bacterial infections of the intestine are caused by various types of bacteria, such as salmonella, shigella, and campylobacter, and can cause symptoms such as diarrhea, abdominal pain, and fever.

Drug interactions

Some of the known drug interactions of metodine df are:

Warfarin: metronidazole may increase the risk of bleeding when taken with the blood thinner warfarin.
Lithium: metronidazole can increase the levels of lithium in the blood, leading to potential side effects.
Disulfiram: the combination of metronidazole and disulfiram can cause a severe reaction characterized by nausea, vomiting, headache, and flushing.
Phenytoin: diloxanide may increase the levels of phenytoin in the blood, leading to potential side effects.

Disease interactions

Some of the known disease interactions of metodine df are:

Blood disorders: metronidazole may worsen blood disorders, including low platelet counts, low white blood cell counts, and anemia.
Neurological disorders: metronidazole may cause neurological side effects such as seizures, numbness, tingling, and dizziness in patients with a history of neurological disorders.
Liver disease: metronidazole and diloxanide are metabolized in the liver, and patients with liver disease may experience an increased risk of adverse effects.
Kidney disease: patients with kidney disease may require dose adjustment or monitoring while taking metodine df.
Pregnancy and breastfeeding: the safety of metodine df during pregnancy and breastfeeding has not been fully established. It is advisable to consult a healthcare professional before using the medication during pregnancy or while breastfeeding.

Food interactions

There are no significant food interactions associated with metodine df tablet, which contains diloxanide and metronidazole. However, patients should avoid consuming alcohol during treatment with metodine df, as it can cause a severe reaction characterized by nausea, vomiting, headache, and flushing.

Patients should take metodine df with a full glass of water and may take it with or without food, as directed by their healthcare professional. However, it is advisable to avoid taking it with dairy products, as they may decrease the absorption of the medication.

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Side effects of metodine-df tablet

Some of the usual side effects of metodine df are:

Nausea and vomiting
Diarrhea
Abdominal pain
Headache
Dizziness
Metallic taste in the mouth
Loss of appetite
Dry mouth
Dark urine
Skin rash or itching

Some less usual but potentially complicated side effects of metodine df include:

Seizures
Outlying neuropathy (insensibility or stinging in the hands or feet)
Encephalopathy (brain disorder)
Liver dysfunction
Blood disorders, including low platelet counts, low white blood cell counts, and anemia

Dosing information

The following is general dosing information for metodine df:

Amoebiasis: for adults, the usual dose is one tablet of metodine df taken three times a day for ten days. Children may require a lower dose based on their weight.
Giardiasis: for adults, the usual dose is one tablet of metodine df taken three times a day for five to seven days. Children may require a lower dose based on their weight.
Bacterial infections: the dosage and duration of treatment may vary depending on the severity and type of infection. It is essential to follow the instructions provided by your doctor or healthcare professional.

Precautions

Never take two doses together, in case of missed dose
If you are allergic to this medication then immediately stop taking the medication
Never take medication if the medicine is expired.
Always complete the treatment as doctor prescribed.
This medication is antibiotic so, if you are allergic to antibiotics then never take this medication with out consultation.

Storage

Metodine df tablet that contains diloxanide (400mg) and metronidazole (500mg) should be stored at room temperature, between 15°c and 30°c (59°f and 86°f), away from direct sunlight, heat, and moisture. It is important to keep the medication in its original packaging until ready to use to protect it from light and moisture.
Metodine df should be keep away from the reach of kids and pets. It should not be stored in the bathroom or other areas where it may be exposed to moisture or humidity.

Packaging

Metodine df tablet that contains active ingredient, diloxanide and metronidazole is available in the form of tablets. The packaging may vary depending on the manufacturer and the country of origin. Typically, metodine df tablets are packaged in a blister pack or a bottle.

The blister pack usually contains 10 tablets, and the bottle may contain 30 tablets or more. The packaging will include information such as the active ingredients, dosage strength, batch number, expiry date, and manufacturer's name and address. It is important to check the packaging for any damage or tampering before taking the medication.

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Price of metodine-df tablet

The price of metodine-df (400mg/500mg) 15 tablets packet is of 123pkr.
The price of metodine-df (250mg/200mg) suspension of 90ml is of 81pkr.
The price of metodine-df (325mg/250mg) 60 tablets packet is of 73pkr.

You can easily buy online medicine In Pakistan and get it delivered to your doorstep with InstaCare. Visit the website or call at 03171777509 for further information.

Source: https://instacare.pk/blog/metodine-df-tablet-uses-side-effects-and-price-in-pakistan

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Frequently Asked Questions

What is the use of Metron DF tablet?

Metron DF tablet is a medication that contains the active ingredient Metronidazole. Metronidazole is an antibiotic that is used to treat a wide range of bacterial and parasitic infections, including: Bacterial infections of the abdomen, such as bacterial peritonitis and liver abscesses Bacterial infections of the skin, such as infected wounds, cellulitis, and acne rosacea Sexually transmitted infections, such as trichomoniasis and bacterial vaginosis Infections caused by anaerobic bacteria, such as Clostridium difficile infections and dental infections Protozoal infections, such as amoebiasis and giardiasis. Metronidazole works by interfering with the DNA of the microorganisms, thereby killing or stopping their growth. DF stands for "Delayed-Release Film-Coated," indicating that the tablet is designed to release the medication slowly over time to improve its effectiveness. It's important to take Metron DF tablet exactly as prescribed by a healthcare professional and to complete the full course of treatment, even if symptoms improve before the medication is finished. Common side effects of Metronidazole may include nausea, vomiting, diarrhea, headache, and metallic taste in the mouth. If you experience any unusual or severe side effects, it's important to contact a healthcare professional.

What is metronide 400mg used to treat?

Metronide 400mg is a medication that contains the active ingredient metronidazole. Metronidazole is an antibiotic that is used to treat a variety of bacterial and parasitic infections, including: Bacterial infections of the abdomen, such as bacterial peritonitis and liver abscesses Bacterial infections of the skin, such as infected wounds, cellulitis, and acne rosacea Sexually transmitted infections, such as trichomoniasis and bacterial vaginosis Infections caused by anaerobic bacteria, such as Clostridium difficile infections and dental infections Protozoal infections, such as amoebiasis and giardiasis. Metronidazole works by interfering with the DNA of the microorganisms, thereby killing or stopping their growth.

Is metronidazole tablet used for loose motion?

Metronidazole is an antibiotic medication that is typically used to treat bacterial and parasitic infections, such as infections of the abdomen, skin, and genital tract. While diarrhea is a symptom of some bacterial and parasitic infections, Metronidazole is not generally used specifically to treat loose motion. However, there may be certain situations where Metronidazole is prescribed for diarrhea caused by a bacterial or parasitic infection. For example, if laboratory tests confirm that the diarrhea is caused by a specific type of bacteria or parasite that is susceptible to metronidazole, a healthcare professional may prescribe this medication to treat the underlying infection.

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