Introduction
Provas-n, is a combination medication that contains paracetamol and orphenadrine citrate. Paracetamol can help reduce pain and fever. Orphenadrine citrate can help stop muscle spasms and pain.
Uses of proves-n tablet
Provas-n is a medicine with two parts. Paracetamol helps with pain and fever. It does this by stopping the body from making chemicals that cause pain and swelling. Orphenadrine citrate stops muscle spasms and stiffness by blocking nerve signals in the body. Together, Provas-n helps to relieve both pain and muscle tension at the same time.
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Drug interactions
here are some of the known drug interactions of provas-n:
- Cns depressants: provas-n can cause drowsiness and impair
cognitive function, so it should not be taken with other central nervous system
(cns) depressants such as alcohol, benzodiazepines, and opioids.
- Anticholinergics: orphenadrine citrate, one of the active
ingredients in provas-n, has anticholinergic effects, so it should not be taken
with other medications that have similar effects, such as antihistamines and
tricyclic antidepressants.
- Monoamine oxidase inhibitors (maois): orphenadrine citrate
should not be taken with maois, which are a type of antidepressant medication,
due to the potential for a dangerous increase in blood pressure.
- Warfarin: paracetamol, another active ingredient in
provas-n, can increase the anticoagulant effect of warfarin, a medication used
to prevent blood clots. Patients taking warfarin should be monitored closely if
they are also taking provas-n.
Disease interactions
Here are some of the known disease interactions of provas-n:
- Glaucoma: orphenadrine citrate, one of the active
ingredients in provas-n, may increase the intraocular pressure in patients with
glaucoma. Therefore, provas-n should be used with caution in patients with
glaucoma.
- Liver disease: paracetamol, another active ingredient in
provas-n, is primarily metabolized in the liver. Patients with liver disease
should use provas-n with caution, and their dosage may need to be adjusted to
avoid potential liver damage.
- Kidney disease: orphenadrine citrate is excreted mainly by
the kidneys, so patients with kidney disease should use provas-n with caution,
and their dosage may need to be adjusted.
- Myasthenia gravis: orphenadrine citrate may worsen the
symptoms of myasthenia gravis, a condition that causes muscle weakness and
fatigue. Therefore, provas-n should be used with caution in patients with myasthenia
gravis.
- Cardiovascular disease: orphenadrine citrate may cause a
decrease in blood pressure, which can be problematic in patients with
cardiovascular disease. Therefore, provas-n should be used with caution in
patients with cardiovascular disease.
Food interactions
It is safe to eat food when taking provas-n. This medicine contains paracetamol and orphenadrine citrate.. In general, it's best to take provas-n with food or milk to help minimize the risk of stomach upset. People taking provas-n should not drink a lot of alcohol or have too much caffeine. These things can make the side effects of the medication worse.
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Side effects of provas-n tablet
Here are some of the usual side effects of provas-n:
- Drowsiness
- Dry mouth
- Dizziness
- Blurred vision
- Nausea and vomiting
- Headache
- Constipation
- Difficulty urinating
- Skin rash
Less usual but more complicated side effects of provas-n may
include:
- Allergic reactions, such as hives, swelling of the face,
lips, tongue or throat, difficulty breathing, or severe itching.
- Increased heart rate
- Severe dizziness or fainting
- Hallucinations or confusion
- Seizures or convulsions
- Liver damage or failure
- Blood diseases, such as less platelet compute or anemia.
Dosage form
Provas-n is a medicine with paracetamol and orphenadrine citrate. It comes in different forms like tablets, capsules, syrups, etc.
- Tablet: provas-n tablets are available in strengths of 450
mg and 325 mg of paracetamol and 35 mg of orphenadrine citrate.
- Injection: provas-n is also available as an injectable
solution containing 30 mg/ml of orphenadrine citrate and 300 mg/ml of
paracetamol.
Dosing information
- The
usual recommended dosage for adults is one to two tablets (450 mg to 900 mg of
paracetamol and 35 mg to 70 mg of orphenadrine citrate) taken three to four
times a day, depending on the severity of the pain and discomfort
- For the injectable form, the usual recommended dose is one
to two ampoules of the solution (300 mg to 600 mg of paracetamol and 30 mg to
60 mg of orphenadrine citrate) every six hours as needed, up to a maximum of 4
ampoules in 24 hours.
Packaging
Provas-n is medicine that comes in two forms. It can be tablets which come in a special package called a blister pack. It also comes as a liquid for injection and that comes in glass containers called ampoules.
- The blister packs for tablets usually contain 10 to 15
tablets per pack, and each tablet is individually sealed in a foil or plastic
blister. The blister packs are often enclosed in a cardboard box with product
information and usage instructions.
- The injectable solution of provas-n is packaged in glass
ampoules containing 2 ml or 5 ml of the solution. The ampoules are typically
packed in cardboard boxes or plastic trays with product information and usage
instructions.
Storage
Keep Provas-n in a place that is cool and dry, not close to the sun, and away from children.
- For the tablets, it's recommended to store them in their
original blister pack or container at a temperature between 20-25°c (68-77°f)
and away from moisture and humidity.
- For the injectable solution, it should be stored in its
original packaging at a temperature between 15-30°c (59-86°f) and protected
from light.
Price of
- Provas-n 450mg/35mg 12 tablets packet is of 625pkr.
- Provas-n 650mg/50mg 10 tablets packet is of 152pkr
- Provas-n 300mg/2ml iv-solution is of 25pkr.
- Provas-n iv 1gm is of 155pkr
