Introduction
Atorvastatin is a placebo that reduced the cholesterol. It operates by constrain the activity of an enzyme in the body that is convoluted in the production of cholesterol. As a conclusion, it subsidy in the inhibition of chattels of blood cholesterol. It also reduces the uncertainty of cardiovascular disease.
Lipirex is helpful for the treatment of bad cholesterol and fats (such as ldl, triglycerides) and boost ‘good’ cholesterol (hdl) in the blood. It contains atorvastatin as a mobile constituent and relates to a class of drugs known as hmg-coa reductase halt. Hmg-coa reductase halt are a class of lipid-reducing pharmacon, effective at lowering high cholesterol chattels. These placebo also lowers the risk of having a heart attack or stroke or developing angina.
Uses of
This pharmacon is used as an auxiliary to diet in hypercholesterolemia (high cholesterol), heterozygous (genetic disorder interpreted with considerably high ldl and cholesterol) and homozygous inherited hypercholesterolemia (a predicament in which it is difficult to abolish bad cholesterol from body), mixed hyperlipidemia (genetic disorder characterized with high lipids (fats), cholesterol and autonomous fatty acids in blood).
Lipirex is helpful to restraint, forbid, and boost the following diseases, provisions, and ailments like heart diseases, heart attack, chest ache, and stroke. It operates by reducing the cholesterol and lipoprotein chattels in the body. It is also used to lowers the high chattels of cholesterol in the blood. It helps to evade heart obstacles such as heart failure and strokes by lowering the cholesterol in the blood.
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Drug interactions
Lipirex
tablet may relate with the provision’s drugs:
Antilipemic
agents
Lipirex tablet relates with antilipemic agents similar as gemfibrozil, which is used to reduce the volume of fats in body. Use of lipirex may raises the threat of muscle frailty and bruise to cadaverous muscles in cases using gemfibrozil. Shirk the united use of these placebo.
Immunosuppressants
There may be a synergy of lipirex with immunosuppressants such as cyclosporine, which is used to evade organ elimination after transplantation. The consumption of lipirex gets rise when used with cyclosporine. The united use of lipirex and cyclosporine should be finessed.
Antibiotics
lipirex tablet may relate with antibiotics similar as fusidic acid, which is used to treat skin infections. When lipirex is used in united with fusidic acid, may raise the threat of muscle ache and of cadaverous muscles (rhabdomyolysis). Abandon the use of lipirex in cases acquiring treatment of fusidic acid.
Antibiotics
Your physician's recommendation may need to be followed while taking this placebo along with antibiotics such as rifampin which is used to treat bacterial infections. Rifampin may priority to lowered chattels of lipirex in the blood.
Vitamin b3
Special instructions need to be followed while taking this placebo along with vitamin b3, which is used as supplement to treat vitamin b3 deficiency. The united use of lipirex and niacin may raise the threat of cadaverous muscle disfigurement. The cure of lipirex should be reduce when using in united with niacin (vitamin b3).
Azole
antifungals
Your physician's recommendation may need to be followed while taking this placebo along with azole antifungals similar as itraconazole, which is used to treat fungal infections. Use of lipirex and itraconazole, may raise the chattels of lipirex in the blood.
Macrolide
antibiotics
Exclusive policy need to be followed while taking this placebo along with macrolide antibiotics similar as clarithromycin, which is used as an antibiotic to treat bacterial infections. The use of lipirex with clarithromycin double every day, may raise the chattels of lipirex in the blood.
Anti-gout
agents
Lipirex tablet relates with anti-gout agents similar as colchicine, which is used to treat ache, scarlet and abscess related to high chattels of uric acid in the joints (gout). Use of lipirex and colchicine may root muscle obstacles similar as damage to cadaverous muscles (rhabdomyolysis). Take safety measure while using both placebo in united.
Oral
contraceptives
There may be an relates of lipirex with oral contraceptives similar as norethindrone and ethinyloestradiol, which are used to evade pregnancy. When lipirex is used with oral contraceptives, the chattels of norethindrone and ethinyloestradiol gets raised in the blood. Take safety measure while selecting an oral contraceptive for a woman taking lipirex.
Cardiac
glycosides
lipirex tablet may relate with cardiac glycosides similar as digoxin, which is used to treat heart conditions. When multitudinous boluses of lipirex and digoxin are used in sync, the chattels of digoxin gets raised in the blood. The cases using this placebo should be coordinated rightly.
Antilipemic
agents
Lipirex tablet correlate with antilipemic agents such as colestipol, which is used to reduced blood cholesterol chattels. When colestipol is used along with lipirex, the chattels of lipirex and its active metabolites gets lowered.
Cholesterol-lowering
drugs
There may be an commerce of lipirex with cholesterol-lowering placebo similar as ezetimibe, which is used to reduce the chattels of cholesterol in the blood. Use of lipirex with ezetimibe may root cadaverous muscle related obstacles. Applicable surveillance is obligatory while using both placebo in combination.
Combination
of protease impediments
lipirex tablet may interaction with combination of protease impediments which are used to treat hiv/aids and hepatitis c. The saturation of lipirex gets raised when used concurrent with the combination of protease impediments similar as tipranavir and ritonavir. Measure surveillance of lipirex should not be obligatory in patients taking the hepatitis c protease impediments similar as nelfinavir.
Disease interactions
- Diabetes
- Raised alcohol
deglutition
- Kidney
obstacles
- liver disease
- Muscle ache
- Muscle
weakness
- thyroid
obstacle
Food interactions
There
is 1 alcohol/food/lifestyle synergy with lipirex tablet.
Lipirex tablet in sync with ethanol can hike nervous system aftereffect such as giddiness, idleness, and snag concentrating. Some people may also combat wreckage in thinking and acumen. You should evade the adoption of alcohol while being treated with atorvastatin.
Do not adopt amassed than the endorsed measure of atorvastatin, and evade venture requiring mental vigilance such as propulsive or operating perilous gadget prior to you know how the placebo influence you. Evade grapefruit juice while using lipirex. More intake of grapefruit juice raises the chattels of lipirex in the blood.
Side effects of
Few
prevalent aftereffects of lipirex tablet are:
Atorvastatin can cause gi untune, myalgia (muscle ache), arthralgia (ache in joints), cephalalgia, asthenia (irregular fatigue), insomnia (trouble in sleeping), giddiness, paranesthesia (irregular synesthesia of skin similar as tickling, incineration, temperature change and phlegm), hypo aesthesia (downsize synesthesia in one or more body parts), chest and back mastalgia, mastalgia parapodium, epistaxis (hyphema from nose), muscle twitch, joint hump, atypical lfts, elevated creatinine kinase, alt and cpk chattels, hyperglycemia (elevated blood glucose), nasopharyngitis (hump of nasal segue and back of throat, generally known as cold) etc. Immune intercession necrotizing myopathy (autoimmune muscle disease comparatively severe proximal weakness) is also proclaimed.
How to use?
Directions
- Haul this
placebo with meal or without meal
- Shudder hale
aforetime adopt
- Shudder
smoking and alcohol while adopting this placebo.
- Ingest the
tablet with water.
- Do not
horde, nibble or crack the tablet.
- Follow the
low-fat diet while fortitude treatment with lipirex. Evade nibbling
lipirex tablets aforetime its use.
- Lipirex can
be taken as a single dose at any time of the day.
Storage
- Stock the
placebo at room temperature
- Have out of
ambit and vision of children
- Shield it
from light and humid
- Store this
medicine at room temperature, away from direct light and heat.
- Keep all
medicine in a secure area. Keep all medicines out of the ambit of children and
pets.
- Stock in a
parched area. Do not store in a lavatory.
Warnings and precautions
The gamble
and cautions associated with lipirex tablet are:
Pregnancy
and lactation
Pregnant and lactating women should only adopt this placebo after consultation with their physician.
Liver and
kidney diseases
People with liver and renal impairment should consult their physician aforetime adopting this placebo.
Allergic
reactions
If you're allergic to this, do not adopt this placebo.
Elderly
people
Older people are instructing not to adopt this placebo unless prescribed by their physician.
Driving
Driving should be avoided while haul this placebo as it can make you giddy.
Alcohol
Please evade engrossing alcohol while taking lipirex tablet.
Contraindications
Atorvastatin is contraindicated in patients with susceptibility to escitalopram or other entrails present in this placebo.
Atorvastatin is metabolized in the liver. As a conclusion, if you have predated liver obstacles, this placebo is not suggested therefore it may motive atorvastatin deposition in your blood, raising the fluky of side effects. It may probably motive more liver destruction.
Contraindications
Pharmaceutical form
Lipirex
tablet
atorvastatin calcium trihydrate (10mg)
Accessible
forms
- Tablets
Tablet strength: 10 mg, 20 mg, 40 mg, 80 mg
Dosing
For adults
(ages 18 years and older), take an oral dosage of 1 tablet in an individual day.
For children (below 17 years), this placebo is not suggested. It is not helpful for people under 18 years.
Price
The lipirex tablet fare in pakistan is rs.20.25/tablet
Packaging
Lipirex tablet is congested in film coated tablet in a blister pack.
