Introduction

Prolexa is a brand name for a medication that contains the active ingredient escitalopram. Escitalopram is an antidepressant medication belonging to the class of drugs known as selective serotonin reuptake inhibitors (ssris). It works by increasing the levels of serotonin in the brain, which helps to improve mood and reduce feelings of anxiety.


Uses of prolexa tablet

Prolexa, is primarily used to treat conditions,

  • Major depressive disorder: prolexa can help improve mood, increase energy levels, and reduce feelings of sadness and hopelessness in individuals with major depression.
  • Generalized anxiety disorder: prolexa can help reduce excessive worrying, tension, and anxiety symptoms in individuals with this disorder.
  • Social anxiety disorder: prolexa can help reduce symptoms of fear or anxiety related to social situations, such as public speaking or meeting new people.

In addition to these primary uses, prolexa may also be prescribed for other conditions, such as panic disorder, obsessive-compulsive disorder, and post-traumatic stress disorder.


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Drug interactions

Some of the drug interactions with prolexa are:

  • Monoamine oxidase inhibitors (maois): using prolexa with maois can cause a life-threatening condition called serotonin syndrome, which can result in rapid heart rate, high blood pressure, fever, seizures, and muscle stiffness.
  • Non-steroidal anti-inflammatory drugs (nsaids): taking nsaids with prolexa may increase the risk of bleeding or bruising.
  • Blood thinners: prolexa can also increase the risk of bleeding when taken with blood thinners.
  • Other antidepressants: using prolexa with other antidepressants, including other ssris, can increase the risk of serotonin syndrome.
  • St. John's wort: this herbal supplement can increase the risk of serotonin syndrome when taken with prolexa.

Disease interactions

Some of the known disease interactions with prolexa are:

  • Liver disease: prolexa is primarily metabolized by the liver, and individuals with liver disease may have a decreased ability to metabolize the drug, which can increase the risk of side effects.
  • Seizure disorders: prolexa can lower the seizure threshold and increase the risk of seizures, particularly in individuals with a history of seizure disorders.
  • Bipolar disorder: prolexa may trigger manic episodes in individuals with bipolar disorder.
  • Bleeding disorders: prolexa can increase the risk of bleeding or bruising in individuals with bleeding disorders or those taking blood-thinning medications.
  • Diabetes: prolexa can affect blood sugar levels and may require monitoring of blood glucose levels in individuals with diabetes.

Food interactions

  • There are no known significant food interactions with prolexa, which contains escitalopram. However, it is important to note that alcohol and grapefruit juice can affect how some medications work in the body, and individuals taking prolexa should avoid consuming large amounts of alcohol or grapefruit juice.
  • Alcohol can increase the risk of side effects such as drowsiness, dizziness, and impaired judgment, while grapefruit juice can increase the amount of escitalopram in the bloodstream and lead to an increased risk of side effects. Therefore, it is recommended to avoid consuming alcohol and grapefruit juice while taking prolexa.

Side effects of prolexa tablet         

Usual side effects of prolexa may include:

  • Nausea
  • Dry mouth
  • Headache
  • Insomnia
  • Dizziness
  • Diarrhea or constipation
  • Increased sweating
  • Sexual dysfunction, such as lessen desire or difficulty attain orgasm
  • Fatigue or weakness
  • Weight differences, for example weight gain or weight loss

Prolexa can cause more complicated side effects, including:

  • Suicidal thoughts or behavior
  • Serotonin syndrome, which is a potentially life-threatening condition that can cause rapid heart rate, high blood pressure, fever, seizures, and muscle stiffness
  • Abnormal bleeding or bruising, particularly in individuals taking blood-thinning medications
  • Low sodium levels in the blood, which can cause symptoms such as weakness, confusion, and seizures

Dosage forms

Prolexa, which contains escitalopram, is available in different dosage forms, including:

  • Tablets: prolexa tablets are available in strengths of 5 mg, 10 mg, and 20 mg. The tablets are usually taken once daily, with or without food, and swallowed whole with water.
  • Oral solution: prolexa oral solution contains 1 mg/ml of escitalopram and is available in 240 ml bottles. The recommended dose is 5 mg once daily, and the solution should be measured with the provided dropper and mixed with water, orange juice or apple juice before taking it.

Dosing information

  • The dosing information for prolexa, which contains escitalopram, may vary depending on the individual's age, medical history, and the condition being treated. The recommended starting dose is typically 10 mg once daily, which can be increased to 20 mg once daily after a few weeks of treatment, based on the individual's response to the medication.
  • For individuals who are elderly, have liver or kidney disease, or are taking other medications that may interact with prolexa, a lower starting dose may be recommended. The dose may also need to be adjusted over time to achieve the desired therapeutic effect and to minimize the risk of side effects.

Storage

Prolexa, which contains escitalopram, should be stored at room temperature, between 20°c and 25°c (68°f and 77°f), in a cool, dry place. The medication should be protected from light, moisture, and excessive heat.


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Packaging

  • Prolexa, which contains escitalopram, is typically packaged in blister packs or bottles, depending on the dosage form. The tablets are usually packaged in blister packs containing 14 or 28 tablets per pack. The oral solution is packaged in a 240 ml bottle with a provided dropper for measuring the dose.
  • The packaging of prolexa typically includes important information such as the dosage strength, dosage form, and instructions for use. It also includes information about potential side effects and precautions that should be taken while taking the medication. The packaging may also include the expiration date and batch number for quality control purposes.

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Source: https://instacare.pk/blog/prolexa-tablet-uses-side-effects-and-price-in-pakistan