Introduction
Zeegap is a brand name medication that contains the active ingredient pregabalin. It belongs to a class of medications called anticonvulsants, which work by decreasing the abnormal activity of the brain that causes seizures and by altering the way that pain signals are transmitted in the nervous system.
Uses of zeegap tablet
Zeegap is a medication that contains pregabalin, which is
used to treat various conditions, including:
- Neuropathic pain: pregabalin is approved by the fda for the
treatment of neuropathic pain associated with conditions such as diabetic
neuropathy, postherpetic neuralgia, and spinal cord injury.
- Epilepsy: pregabalin is also used in the treatment of
partial seizures in adults with epilepsy.
- Generalized anxiety disorder (gad): pregabalin is
fda-approved for the treatment of gad.
- Fibromyalgia: pregabalin is used to treat fibromyalgia, a
chronic condition characterized by widespread pain, fatigue, and other
symptoms.
- Restless leg syndrome: pregabalin is used off-label to treat
restless leg syndrome, a neurological disorder that causes uncomfortable
sensations in the legs and an irresistible urge to move them.
Drug interactions
Some of the drugs that may interact with zeegap include:
- Cns depressants: zeegap can enhance the effects of cns
depressants such as opioids, benzodiazepines, and alcohol, leading to increased
sedation and respiratory depression.
- Antidiabetic drugs: pregabalin can increase the risk of
hypoglycemia when used concomitantly with antidiabetic drugs such as insulin
and sulfonylureas.
- Thiazolidinediones: pregabalin can cause fluid retention and
edema when used concomitantly with thiazolidinediones, such as rosiglitazone
and pioglitazone.
- Angiotensin converting enzyme inhibitors (aceis): pregabalin
can increase the risk of angioedema when used concomitantly with aceis such as
enalapril and lisinopril.
- Narcotic analgesics: pregabalin can enhance the effects of narcotic analgesics such as oxycodone and hydrocodone.
Disease interactions
Some of the medical conditions that may interact with zeegap
include:
- Kidney disease: pregabalin is primarily eliminated by the
kidneys, and its clearance is reduced in patients with impaired renal function.
Therefore, the dosage of zeegap may need to be adjusted in patients with renal
impairment.
- Depression: zeegap may worsen symptoms of depression and may
increase the risk of suicidal thoughts or behaviors, especially in patients
with a history of depression or suicidal ideation.
- Bleeding disorders: pregabalin may increase the risk of
bleeding in patients with bleeding disorders or those taking anticoagulant
medications.
- Hypersensitivity: zeegap may cause hypersensitivity
reactions, such as rash, hives, and angioedema, in patients who are allergic to
pregabalin or any of its components.
- Respiratory disease: zeegap may cause respiratory depression
or exacerbate respiratory depression in patients with respiratory disease, such
as chronic obstructive pulmonary disease (copd) or sleep apnea.
Food interactions
There are no known food interactions with zeegap (pregabalin). However, taking zeegap with food may slow down the absorption of the medication and delay its onset of action. It is recommended to take zeegap on an empty stomach, at least 1 hour before or 2 hours after a meal.
View More: Angised Tablet - Uses Side Effects And Price In Pakistan
Side effects of zeegap tablet
Some usual side effects of zeegap include:
- Dizziness
- Somnolence (feeling sleepy)
- Dry mouth
- Blurred vision
- Edema (swelling)
- Weight gain
- Difficulty concentrating
- Confusion
- Headache
- Nausea and vomiting
Less usual but more complicated side effects of zeegap may
include:
- Suicidal thoughts or behaviors
- Allergic reactions (such as hives, rash, and itching)
- Angioedema (inflammation of the face, mouth, and gullet)
- Severe muscle pain or weakness
- Unusual bleeding or bruising
- Decreased platelet counts
- Worsening of depression or anxiety symptoms
- Hallucinations or delusions
Dosage form
It is accessible in dissimilar dosage forms, are:
- Capsules: pregabalin capsules are available in strengths of
25mg, 50mg, 75mg, 100mg, 150mg, 200mg, 225mg, and 300mg. The capsules are
usually taken orally, with or without food, as directed by your doctor.
- Oral solution: pregabalin oral solution is available in a
concentration of 20mg/ml. It is usually taken by mouth using a measuring device
or syringe to ensure accurate dosing.
- Extended-release tablets: pregabalin extended-release
tablets are available in strengths of 82.5mg, 165mg, and 330mg. They are
designed to release the medication slowly over time, providing a steady dose
throughout the day.
Dosing information
The dosing of zeegap (pregabalin) depends on the medical
condition being treated, the patient's age, kidney function, and other factors.
Your healthcare provider will determine the appropriate dose for you and may
adjust it as necessary.
- For the treatment of neuropathic pain associated with
diabetic peripheral neuropathy, the recommended dose is 50 mg to 100 mg three
times daily, or 75 mg twice daily, with a highest dose of 300 mg per day.
- For the management of postherpetic neuralgia, the
recommended dose is 75 mg to 150 mg twice daily, or 50 mg to 100 mg three times
daily, with a highest dose of 300 mg per day.
- For the treatment of fibromyalgia, the recommended dose is
300 mg to 450 mg per day, given in two or three divided doses.
- For the treatment of partial onset seizures in adults, the
recommended dose is 150 mg to 600 mg per day, divided into two or three doses.
- For the management of generalized anxiety disorder, the
recommended dose is 150 mg to 600 mg per day, divided into two or three doses.
Packaging
Pregabalin is a prescription medication and is typically dispensed in a bottle or blister pack, with each dosage form having its own specific packaging. The packaging will typically include important information such as the strength of the medication, the dosage instructions, the expiration date, and any warnings or precautions.
The packaging may also include additional information such as the manufacturer's name and contact information, the drug's national drug code (ndc) number, and any patient information leaflets or inserts that provide further details about the medication.
Storage
Pregabalin should be stored at room temperature between 68-77 degrees fahrenheit (20-25 degrees celsius). It should be kept in a cool, dry place away from moisture, heat, and direct sunlight, and keep away from children.
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