Abu Bakar Lab ICT Malaria Test Price and Details

Last Updated On Sunday, November 17, 2024

What is the ICT malaria Test?

Rapid immunochromatographic assay in test card form is the ICT Malaria P.f./P.v. test. Both a panmalarial antigen and the histidine-rich protein 2 antigen (HRP2), which is exclusive to Plasmodium falciparum, are found in the assay.

When is an ICT malaria performed?

In a nutshell, 10 µl of whole blood is placed on a sampling pad with antibodies tagged with colloidal gold, then a buffer reagent is used to cause cell lysis. The panmalarial antigens and releasing HRP2 bind to the antibodies on the pad. Antibody complexes that have been tagged with an antigen move along the test strip and pass two test lines as well as a control line.

Whether or whether the panmalarial antigen line is detected, the diagnosis is P. falciparum-positive if the HRP2-specific line is evident. The test is regarded as suggesting a P. falciparum mono-infection or a mixed infection of P. falciparum and non-P when all three lines are seen. falciparum. The sample is positive for a malaria parasite other than P. falciparum if only the controls and panmalarial antigen lines are present.

What does ICT malaria detect?

ICT An in vitro diagnostic test for the quick detection of P. falciparum antigens in circulation (HRPII antigen) and an antigen shared by all four species of malaria is known as the malaria combo cassette test (aldolase antigen). On the outside of P-parasitic red blood cells, HRPII is highly expressed.

What are the benefits of this test?

The great sensitivity of ICT, lack of specialist training, and shorter test duration (10–15 minutes) are some of its benefits. In samples with a parasite density of fewer than 50 parasites/ml, the claimed sensitivity of ICT kits is in the region of 50-70%, whereas for samples with such a parasite density of 50-100 parasites/ml, it is > 90%.

When should I know the results of the ICT malaria test?

There are currently commercially accessible rapid diagnostic procedures for the identification of malaria antigens, such as dipstick format kits. Rapid dipsticks show good particularity and sensitivity when compared to traditional microscopy, according to several recent investigations.  A novel immunochromatographic test kit that can identify Plasmodium (P.) falciparum and P. vivax (P.f/P.v) antigens have recently been released. This is the malaria P.f/P.v immunochromatographic test (ICT). 

The panmalarial antigen and P. falciparum-specific antigen are what the test looks for. Two colloid gold-labeled antibodies that have been immobilized throughout the test strip are used in the test. One antibody is particular to the P. falciparum trophozoite and young gametocyte-produced histidine-rich protein 2 (HRP-2) antigen, a water-soluble protein. The second antibody is particular to an antigen that all Plasmodium types share. ICT Malaria test results are due in 2 days (s). You will be informed when the results are published following processing. You could either visit a nearby collecting samples site to acquire printed reports or you can obtain your lab test results online.

ICT malaria Test Results range?

The ICT Malaria test is a medical evaluation of your health that is done in medical testing facilities. Your ICT Malaria sample will be collected by the lab and processed there for this test. The ICT test had a sensitivity of 81.5% and a specificity of 81.9% for detecting Plasmodium spp. infection, whereas P. falciparum was diagnosed with a sensitivity of 69.7% and a specificity of 73.7%. With larger parasitemias, the ICT test became more sensitive.